Imipenem Resistance in Clostridium difficile Ribotype 017, Portugal

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Imipenem Resistance in Clostridium difficile Ribotype 017, Portugal

We describe imipenem-resistant and imipenem-susceptible clinical isolates of Clostridium difficile ribotype 017 in Portugal. All ribotype 017 isolates carried an extra penicillin-binding protein gene, pbp5, and the imipenem-resistant isolates had additional substitutions near the transpeptidase active sites of pbp1 and pbp3. These clones could disseminate and contribute to imipenem resistance.

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 2018

ISSN: 1080-6040,1080-6059

DOI: 10.3201/eid2404.170095